a medical condition in which some or all of the sutures in the skull of an infant close too early
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: - informed consent from the parents - no syndromic diagnosis (i.e. additional congenital anomalies besides the craniosynostosis) - aged between 3 and 12 months - regarding trigonocephaly: moderate and severe presentation for which surgery is considered
Exclusion criteria
Exclusion criteria: - no informed consent from the parents - syndromic diagnosis - older than 12 months of age - mild trigonocephaly
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main parameters are the DTI and ASL data and ophthalmologic data from the black bone MRI, and the psychological test data taken at 2, 4, and 6 years of age. The inclusion of patients for black bone MRI stops after 2 years if a sufficient number of patients is included, while the study stops once the last included patient has had its final psychological assessment at 6 years of age. | — |
Countries
Netherlands
Outcome results
None listed