Hemodynamic characterization of cardiac disease and aortopathy in congenital heart disease: a 4D flow MRI study

Hemodynamic characterization of cardiac disease and aortopathy in congenital heart disease: a 4D flow MRI study - 4D flow in patients with congenital heart disease.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46219

Enrollment

180

Registered

2016-02-04

Start date

2016-02-19

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with bicuspid aortic valve disease, coarctation of the aorta, patients with fontan circulation or patients with aortic dilatation

Exclusion criteria

Exclusion criteria: A subject is excluded from participation in the study when meeting the following criteria:;- Unable to provide informed consent. - Metal objects inside the body. - Pregnant women. - Claustrophobia.

Design outcomes

Primary

Measure	Time frame
BAV patients Shear stress in the ascending aorta Energyloss near the aortic valve. Flow patterns in the ascending aorta CoA patients Shear stress in the ascending aorta, CoA repair site, and descending aorta. Energyloss near the CoA repair site. Flow patterns in the aorta ascendens Fontan patients Eenergy loss in the cavo-pulmonal circulation Aortic dilatation Shear stress in the ascending aorta Flow patterns in the ascending aorta	—

Measure

Time frame

BAV patients Shear stress in the ascending aorta Energyloss near the aortic valve. Flow patterns in the ascending aorta CoA patients Shear stress in the ascending aorta, CoA repair site, and descending aorta. Energyloss near the CoA repair site. Flow patterns in the aorta ascendens Fontan patients Eenergy loss in the cavo-pulmonal circulation Aortic dilatation Shear stress in the ascending aorta Flow patterns in the ascending aorta

—

Countries

Netherlands

Outcome results