Liking of e-liquid flavors: correlation between smelling and vaping

Liking of e-liquid flavors: correlation between smelling and vaping - Smell-e

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON46212

Enrollment

Registered

2018-07-05

Start date

2018-11-13

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perceptie attractiveness liking

Interventions

Research subjects will be exposed to the odor of 25 e-liquids (divided over two smelling sessions) and the vapor of the same 25 e-liquids (divided over two vaping sessions).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Good proficiency of the Dutch language - Aged 18 to 55 years at the time of inclusion - Healthy as defined by the F1 Screening questionnaire - Normal olfactory function according to Sniffin* Sticks identification test (>12 correct answers out of 16)

Exclusion criteria

Exclusion criteria: - Having ever used an e-cigarette - Pregnancy (plans) or lactating - Being allergic for any of the products under investigation in this study (e-liquid flavors) - Being employed by the Division of Human Nutrition of Wageningen University or doing an MSc internship/writing a thesis at the Sensory Science and Eating Behavior chair group within the Division of human Nutrition of Wageningen University - Participating in another medical-scientific study (except for EetMeetWeet)

Design outcomes

Primary

Measure	Time frame
The primary study parameter is the correlation coefficient of liking of e-liquid flavors through smelling versus liking of e-liquid flavors through vaping, for smokers as well as for non-smokers.	—

Secondary

Measure	Time frame
Secundary study parameters are: - Difference in correlation coefficient of liking by smelling and liking by vaping between smokers and non-smokers. - Correlation coefficients of intensity, familiarity, and irritation of e-liquid flavors by smelling versus vaping, for smokers as well as for non-smokers. - Average (mean+SE) liking, intensity, familiarity, and irritation of the e-liquids used in this study, including differences (p-value) between e-liquids, for smelling as well as for vaping. In addition, a distinction will be made between male and female research subjects. - Slope and intercept for the relation between liking by smelling and liking by vaping, within research subjects. - Correlation coefficients between average liking, intensity, familiarity, and irritation, for smelling as well as for vaping.	—

Measure

Time frame

Secundary study parameters are: - Difference in correlation coefficient of liking by smelling and liking by vaping between smokers and non-smokers. - Correlation coefficients of intensity, familiarity, and irritation of e-liquid flavors by smelling versus vaping, for smokers as well as for non-smokers. - Average (mean+SE) liking, intensity, familiarity, and irritation of the e-liquids used in this study, including differences (p-value) between e-liquids, for smelling as well as for vaping. In addition, a distinction will be made between male and female research subjects. - Slope and intercept for the relation between liking by smelling and liking by vaping, within research subjects. - Correlation coefficients between average liking, intensity, familiarity, and irritation, for smelling as well as for vaping.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)