Pain management after laparoscopic donor nephrectomy / keyhole surgery to remove a kidney
Conditions
Interventions
Patients will be randomly assigned in a 1:1 fashion to postoperative pain
management with patient controlled sublingual sufentanil tablets or patient
controlled intravenous morphine.
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Scheduled for living kidney donation * Obtained informed consent * Age *18 years
Exclusion criteria
Exclusion criteria: * Inability to understand or follow instructions of use * Contra-indications for patient controlled analgesia or opiates * Chronic use of opiates * Moderate to severe liver insufficiency (Child-Pugh score * 7) * Severe renal insufficiency (eGFR 35 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Independent mobilization (defined as patient reported use of the ward corridor bathroom without assistance) on postoperative day 1. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery on postoperative day 1 (QoR-40 questionnaire), quantitative mobilization measurements (HealthPatch® measured body posture and number of steps), heart rate variability, pain scores, postoperative nausea and vomiting, total dose of analgesics and anti-emetics, drug side effects, postoperative complications, length of hospital stay, re-admission within 30 days, ease of care nurse questionnaire and global daily cost of care. | — |
Countries
Netherlands
Outcome results
None listed