acute myeloid leukaemia blood cancer
Conditions
Interventions
Patients will do 4 sessions of real or sham CBM ( half/half randomly assigned)
within one week (7 days) time.
acute myeloid leukaemia
anxiety
depression
distress
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Subjected to the ward of the department of hematology-oncology for treatment of a AML - Hightened level of distress as measured with the *Distress Thermometer*. A *Distress Thermometer* score of 5 or higher was originally recommended as denoting significant distress necessitating psychosocial referral (National Comprehensive Cancer Network, 2005). Patients with a score of 8 or higher in the HADS will be considered for participation in the study. (HADS; Zigmond & Snaith, 1983). This cut-off shows good sensitivity and specificity in a somatic patient population (Bjelland et al., 2002). - Signed IRB-approved informed consent form
Exclusion criteria
Exclusion criteria: - Impossibility to obtain a valid informed consent - Severe depression or other psychiatric disorders that interfere with the ability to receive a cognitive intervention of 20 minutes per day - Insufficient comprehension of the Dutch language - IQ estimate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters are change in affective (i.e., depression and anxiety) and distress symptoms as measured by the HADS and the DASS 21. All primary measures are sampled before and directly after as well as 1 week after the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| earlier life stress, psychological and cognitive aspects, and coping abilities may modulate the vulnerability. Impact of these variables on the primary outcome will be a secondary endpoint as well as individual clinical progression of each individual patient after three- four weeks of treatment. | — |
Countries
The Netherlands
Outcome results
None listed