Detection of Treponema pallidum DNA at various body locations

Detection of Treponema pallidum DNA at various body locations - The presence of syphilis bacteria at various body locations

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46109

Enrollment

285

Registered

2018-09-26

Start date

2018-11-26

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Syphilis Treponema pallidum

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -18 years or older - Being male and have had sex with males in the past 6 months

Exclusion criteria

Exclusion criteria: Exclusion criteria - Use of antibiotics within 4 weeks prior to inclusion - Use of antibiotics within 12 weeks after inclusion in participants with positive Tp-PCR results

Design outcomes

Primary

Measure	Time frame
The presence of Tp-DNA load in pharyngeal, rectal, urine and peripheral blood samples; RPR syphilis titer, and infection stage	—

Secondary

Measure	Time frame
Sensitivity, specificity, predictive values (positive and negative) and area under the curve (AUC) of the Tp-PCR assay in pharyngeal, rectal, urine and blood samples.	—

Countries

Netherlands

Outcome results