Investigation on the effect of shear loading on cytokine release of human skin

Investigation on the effect of shear loading on cytokine release of human skin - Effect of shear loading on cytokine release

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON46047

Enrollment

Registered

2017-05-24

Start date

2017-08-23

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pressure ulcers

Interventions

Skin

The intervention is the application of different shear loads at a constant normal pressure. The applied shear loads are 1.2 kPa (9 mmHg), 2.4 kPa (18 mmHg), and 4.8 kPa (36 mmHg). The normal pressur

Cytokine

Decubitus

Shear

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: healthy age between 18 and 35.

Exclusion criteria

Exclusion criteria: History of skin affection Skin trauma at the volar aspect of the forearm

Design outcomes

Primary

Measure	Time frame
The main study parameter is the increase in IL-1a concentration for different values of shear loading.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)