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Medication Review in patients with Polypharmacy in primary care: Effects of the Clinical Rules Engine and the Outcome Prioritisation Tool on Patient and Clinical Outcomes: CRE-OPT study

Medication Review in patients with Polypharmacy in primary care: Effects of the Clinical Rules Engine and the Outcome Prioritisation Tool on Patient and Clinical Outcomes: CRE-OPT study - CRE-OPT study

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON46017
Enrollment
360
Registered
2018-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polyfarmacie daily use of 5 medications or more Polypharmacy

Interventions

Intervention: integral medication review including a consultation with GP, augmented with sophisticated medication review software (*Clinical Rules Engine* (CRE)) and including an explicit assessmen
GPs are roughly informed about the intervention and are stimulated to evaluate the prescribed medication of the patients participating in the study, in their usual way.

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients aged * 60 years with at least 5 chronic medication prescriptions in at least two different organ systems.

Exclusion criteria

Exclusion criteria: Patients who cannot act for themselves, patients with insufficient knowledge of Dutch language, patients with a life-expectancy of less than one year.

Design outcomes

Primary

MeasureTime frame
The primary outcome measure is treatment satisfaction measured with the Treatment Satisfaction Questionnaire for Medication (TSQM-II). .

Secondary

MeasureTime frame
Secondary outcome measures are: a. Patient related: medication adherence, measured with the Medication Adherence Report Scale (MARS-5), and quality of life measured with EQ-5D . b. Medication related: Drug Burden Index, changes in medication prescriptions, number and type of alerts (all extracted by CRE). c. Process related: time needed in general practice (by GP and nurse practitioner) and by the community pharmacist; number of contacts between GP and medical specialist to discuss medication changes; satisfaction of patients and professionals with CRE-OPT.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)