Attentional interference by itch and pain

Attentional interference by itch and pain - Attentional interference by itch and pain

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46015

Enrollment

Registered

2017-10-20

Start date

2017-06-21

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aandoeningen die gepaard gaan met (chronische) jeuk en pijn Itch pruritus

Interventions

Attentional processes

Itch

Pain

Pruritus

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Healthy volunteer* 18-30 years old* fluent in Dutch language

Exclusion criteria

Exclusion criteria: Severe or long-term physical or psychiatric morbidity (e.g., multiple sclerosis, diabetes mellitus, heart or lung disease, rheumatoid arthritis, vasculitis, major depressive disorder, atopic dermatitis, migraine), use of pacemaker, chronic itch or pain complaints, current use of medication (e.g., antihistaminics, analgesics), pregnancy.

Design outcomes

Primary

Measure	Time frame
Behaviourally, attentional interference, reflected by reaction times and accuracy for visual targets during the SAT, will be compared between itch and pain stimulation and vibrotactile stimulation. Neurophysiologically, attentional interference, reflected by EEG alpha desynchronization, will be compared between itch and pain stimulation compared to vibrotactile stimulation.	—

Secondary

Measure	Time frame
Secondary outcomes of the study, on a behavioural level, are interaction effects between stimulus type (itch, pain, vibrotactile control) and congruency (congruent: attention directed ipsilaterally to the stimulation & incongruent: attention directed contralaterally to the stimulation), which will be explored over the time course of the somatosensory stimuli during the SAT. On a neurophysiological level, EEG alpha desynchronization over the time course of the somatosensory stimulation, irrespective of the SAT, will be investigated. Exploratory, EEG alpha desynchronization over the time course within the blocks during the SAT will also be investigated. Other study parameters are the results of both computerized behavioural attention tasks, i.e. the dot-probe task for itch measuring attentional processing of itch pictures and the Flanker task measuring attentional interference in general. In addition, the relationship between the individual characteristics potentially related to attentional itch and pain processing and the outcomes of the behavioural attention tasks will be explored.	—

Measure

Time frame

Secondary outcomes of the study, on a behavioural level, are interaction effects between stimulus type (itch, pain, vibrotactile control) and congruency (congruent: attention directed ipsilaterally to the stimulation & incongruent: attention directed contralaterally to the stimulation), which will be explored over the time course of the somatosensory stimuli during the SAT. On a neurophysiological level, EEG alpha desynchronization over the time course of the somatosensory stimulation, irrespective of the SAT, will be investigated. Exploratory, EEG alpha desynchronization over the time course within the blocks during the SAT will also be investigated. Other study parameters are the results of both computerized behavioural attention tasks, i.e. the dot-probe task for itch measuring attentional processing of itch pictures and the Flanker task measuring attentional interference in general. In addition, the relationship between the individual characteristics potentially related to attentional itch and pain processing and the outcomes of the behavioural attention tasks will be explored.

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Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)