induction of ventricular arrhythmias
Conditions
Interventions
Both the conventional and the short protocol will be performed in each study
patient. The order in wich the protocols are performed will be determined in a
random fashion. If sustained monomorphic V
Sponsors
Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with left-dominant NICM with previous documentation of sustained VA (sustained monomorphic VT or VF) or clinically considered to be at high risk for VA (presenting with palpitations or syncope with/or without documented non-sustained VT) scheduled for electrophysiological study with/or without ablation.
Exclusion criteria
Exclusion criteria: - Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoints are 1) Reproducible induction (two times) of sustained monomorphic VT (lasting longer than 30 seconds or requiring immediate termination because of hemodynamic instability), 2) Induction of two episodes of polymorphic VT or VF requiring cardioversion or 3) Non inducibility of any sustained VA from two ventricular sites. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints of the study are: - to compare the efficiency (in terms of time-to-induction or to time-to-complete the induction protocol) of the conventional versus short protocol of induction. - in patients scheduled for endocardial VT ablation, the additional yield of induction from a left ventricular (LV) site will be tested - in patients scheduled for endo- and epicardial VT ablation, the additional yield of induction from an epicardial site will be tested | — |
Countries
Netherlands
Outcome results
None listed