Titrating to the optimal pressure. Is transcutaneous electromyography of the diaphragm a good measurement to determine the optimal respiratory support, during continuous positive airway pressure (CPAP), in pre-term born neonates.

Titrating to the optimal pressure. Is transcutaneous electromyography of the diaphragm a good measurement to determine the optimal respiratory support, during continuous positive airway pressure (CPAP), in pre-term born neonates. - Optimal pressure during CPAP measured through dEMG in pre-term neonates

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON45956

Enrollment

Registered

2017-07-20

Start date

2019-01-24

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory support support of breathing

Interventions

a stepwise in- and decrement of level of CPAP, between 4-8 cm H20, in blocks of 10 minutes.

CPAP

electromyography

Neonate

non-invasive respiratory support

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: - pre-term neonates admitted to the NICU ward. - supported with CPAP - clinically stable, for at least 24 hours - gestational age above 26 weeks and under 32 weeks

Exclusion criteria

Exclusion criteria: - neonates with congenital anomalies - respiratory support other than CPAP - gestational age under 26 weeks and above 32 weeks

Design outcomes

Primary

Measure	Time frame
Changes in dEMG signal ( in uV); measuring the maximal, minimal and delta ( difference between de maximum and minimum value) values of the dEMG during the levels of CPAP. Silverman/ Anderson score measured at 5 and 10 minutes per block.	—

Secondary

Measure	Time frame
- Vital parameters: heart frequency, saturation, apnea, breathing frequency	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)