Articulation and Coordination of Speech in Parkinson*s Disease

Articulation and Coordination of Speech in Parkinson*s Disease - Articulation and Coordination of Speech in PD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45931

Enrollment

Registered

2018-07-19

Start date

2019-04-25

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - At least 18 years of age - Mother tongue speaker of Dutch;Only for the PD group: - Diagnosed with idiopathic Parkinson*s disease (according to the UK Parkinson*s Disease Society Brain Bank Clinical Diagnostic Criteria)

Exclusion criteria

Exclusion criteria: - Older than 80 years of age - A score of 2 or higher on part 1.1 (cognitive impairment) or part 1.2 (hallucinations and psychosis) of the UPDRS - History of neurological or psychological disorders - Self-reported signs of depression - Self-reported swallowing problems - Stuttering or other speech and language problems - Non removable metal on, in or close to the head (e.g., piercings, dental braces, medical devices such as deep brain stimulation electrodes)

Design outcomes

Primary

Measure	Time frame
The main study endpoints parameters are: - Displacement of the tongue tip, the tongue body, the lips and the jaw at consonant and vowel targets. - Velocity of tongue of the tongue tip, the tongue body, the lips and the jaw at key landmarks of speech gestures. - Duration of speech gestures produced with of the tongue tip, the tongue body, the lips and the jaw. - Speech rate (syllables/min and words/min).	—

Measure

Time frame

The main study endpoints parameters are: - Displacement of the tongue tip, the tongue body, the lips and the jaw at consonant and vowel targets. - Velocity of tongue of the tongue tip, the tongue body, the lips and the jaw at key landmarks of speech gestures. - Duration of speech gestures produced with of the tongue tip, the tongue body, the lips and the jaw. - Speech rate (syllables/min and words/min).

—

Secondary

Measure	Time frame
The secundary study endpoints parameters are: - F1 and F2 formant measures during the production of vowels (acoustic) - Intensity of the speech signal during the production of stops (acoustic)	—

Countries

Netherlands

Outcome results