Diabetes type 2 metabolic diseases
Conditions
Interventions
Addition of 10% arabinose to a sucrose drink.
And we will explore the addition of 15% of arabinose to a normal diet.
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Age between 55-80 years * BMI * 25.0 kg/m2 * Impaired fasting glucose (IFG; fasting glucose * 5.6 and
Exclusion criteria
Exclusion criteria: * Diagnosed diabetes, * Diagnosed liver, pancreas or endocrine diseases which could affect the study results, * Having gastro-intestinal problems, * Use of medication or supplements which could affect the study results (Moreover, chronic medication and supplements should be used as normal when they donot affect the study results), * Allergy, intolerance or oversensitivity for food products, * Sensitive to medical skin adhesives, * Following a medically prescribed, low energy or low carbohydrate diet, * Unwilling to consume the provided diets, * >5 kg weight change during the last 3 months, * Current antibiotics usage or in the two months prior to the screening session, * Excessive alcohol consumption (>21 glasses/week on average for men and >14 glasses/week for women), * Having blood vessels that are too difficult for inserting a cannula, as judged by the study nurse, * Not normal haemoglobin (Hb) concentration:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycaemic response | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin response, glucagon response, satiety response, glucose monitoring, gastro-intestinal tolerance | — |
Countries
Netherlands
Outcome results
None listed