clinical depression major depression
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria patient sample;a) Primary diagnosis of major depression according to DSM-V criteria ;Inclusion criteria healthy control sample;b) No lifetime diagnosis of/treatment for depression or other psychopathology c) Normal/subclinical scores on dimensional measures of psychopathology
Exclusion criteria
Exclusion criteria: a) Psychoses, mania, Tourette*s syndrome, obsessive-compulsive disorder b) Major internal or neurologic disorder c) Traumatic head injury d) Current substance abuse or dependence requiring treatment e) Evidence of acute suicidal risk requiring intervention f) MRI contradictions such as metal implants en claustrophobia g) Left-handedness h) Pregnancy i) Insufficient knowledge of Dutch language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - MRI data on structural/functional properties of deep-lying subcortical brain regions - Clinical phenotypes of depression - (Epi)Genetic data on relevant neurotransmitter systems | — |
Countries
Netherlands
Outcome results
None listed