High-field MRI of the compression of the anterior visual pathway in pituitary adenoma

High-field MRI of the compression of the anterior visual pathway in pituitary adenoma - 7T MR imaging of pituitary macro adenoma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45804

Enrollment

Registered

2018-01-29

Start date

2018-04-18

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

macroadenoma Pituitary tumour

Interventions

Macroadenoma

Pituitary

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with a pituitary macro adenoma

Exclusion criteria

Exclusion criteria: 1. Age 70 years 2. Renal failure or previous allergic reactions to contrast agent 3. Known pathology that could simultaneously effect visual fields e.g. glaucoma 4. Contraindications to MRI scanning, including: a. Claustrophobia b. Pregnancy c. Pacemaker and defibrillator d. Nerve stimulators e. Intracranial clips f. Metallic fragments g. Ferromagnetic implants h. Hydrocephalus pump i. Permanent make-up j. Tattoos situated above the shoulder region k. Piercings that cannot be removed l. Subjects who are unable to lie still e.g. due to Tremor, Parkinson*s disease m. Severe physical disability (completely wheelchair bound)

Design outcomes

Primary

Measure	Time frame
Radiological descprition of the optic-chiasmatic system, this will lead to the evaulation of: -The configuration of the anterior optic pathway/optic chiasm Ophthalmic description: -Thickness of the optic-nerve fibre layer on OCT -Visual field defect noted on Humphrey analyser -Visual acuity through EDTRS-chart -Visual functioning questionnaire	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)