Frontal cerebral hemodynamic changes in adults after mild traumatic brain injury using Functional NearInfrared Spectroscopy (fNIRS); a pilot study.

Frontal cerebral hemodynamic changes in adults after mild traumatic brain injury using Functional NearInfrared Spectroscopy (fNIRS); a pilot study. - fNIRS in adults after mild traumatic brain injury.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45790

Enrollment

Registered

2017-07-19

Start date

2019-07-19

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(Licht) traumatisch hersenletsel Mild traumatic brain injury - concussion

Interventions

adults

fNIRS

mild traumatic brain injury

outcome

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Traumatic brain injury Glasgow Coma Scale score 13-15 at Emergency Department admittance Age 18 years and older Recovered from posttraumatic amnesia (PTA) Informed consent by patient

Exclusion criteria

Exclusion criteria: No permanent residence Intoxication with or addiction to alcohol and/or drugs Previous admission for traumatic brain injury Psychiatric illness including depression Epilepsia Severe hypoxia, hypercapnia or anemia Neurodegenerative disease No comprehension of Dutch language

Design outcomes

Primary

Measure	Time frame
Primary outcome measures: a) (Changes in) frontal cerebral perfusion measured using fNIRS (including cognitive tasks) in patients compared to healthy controls. b) Functional outcome three months post-injury, determined using the Glasgow Outcome Scale Extended (GOSE).	—

Secondary

Measure	Time frame
Secondary outcome measures: a) Functional outcome six weeks post-injury, determined using the Glasgow Outcome Scale Extended (GOSE). b) Post-traumatic complaints two weeks and three months post-injury determined using the Groningen Klachtenlijst.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)