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The anabolic response following ingestion of a plant-based protein product in vivo in healthy young men

The anabolic response following ingestion of a plant-based protein product in vivo in healthy young men - Plantbased protein project

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON45741
Enrollment
34
Registered
2017-04-06
Start date
2017-06-23
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gezonde voeding muscle growth Muscle hypertrophy

Interventions

Subjects will either consume 40 g wheat- or chicken protein (isonitrogenous amount) in the form of a ready-to-eat product. Both meals will be baked for 8 minutes with 3 ml of olive oil and served on

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Males * Aged between 18 - 35 years * Healthy, recreationally active (max 3 days per week performing activities) * BMI 18.5 * 27.5 kg/m2

Exclusion criteria

Exclusion criteria: * Females * Diagnosed Diabetes * Wheat allergy * Celiac disease * Smoking * Diagnosed metabolic or intestinal disorders * A history of neuromuscular problems * Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). * Participation in structured resistance exercise program

Design outcomes

Primary

MeasureTime frame
The main study endpoint is the fractional synthetic rate (FSR) of muscle protein synthesis In order to determine the FSR, the following parameters will be measured: * Muscle protein-bound L-[ring-13C6]-phenylalanine enrichments (expressed as MPE) * Muscle tissue-free L-[ring-13C6]-phenylalanine enrichments (expressed as MPE) * Plasma L-[ring-13C6]-phenylalanine enrichments (expressed as MPE)

Secondary

MeasureTime frame
Amino acid concentrations, glucose and insulin concentrations GI-complaints and palatability after ingestion of the meals (VAS questionnaire)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)