lokale ontstekingsreactie als gevolg van een lokale afgebakende infectie in een gebitselement apical periodontitis root tip inflammation
Conditions
Interventions
Teeth are treated with a non-surgical root canal treatment (NSRCT with RISA
irrigation. During a NSRCT RISA is going to be used instead of the currently
employed 2%-sodium hypochlorite solution, to
endodontic
postoperative
root canal treatment
Sponsors
Academisch Centrum Tandheelkunde Amsterdam (ACTA)
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - apical periodontitis has been diagnosed and confirmed with an intra-oral radiograph and appears on the radiograph as a radiolucent area around one or more root tips of the affected tooth. A root canal treatment has a reasonable/good prognosis (Sjögren et al. 1990) and the subject prefers NSRCT over tooth extraction or monitoring. The affected tooth has not previously received a complete root canal treatment. - no spontaneous pre-operative pain or spontaneous pre-operative pain less than 36 - no or mild swelling - if present, draining or no-draining sinus tract - 18 - 75 years. - completed the medical history questionnaire. - all teeth except third molars - DPSI of subject tooth is
Exclusion criteria
Exclusion criteria: Subject tooth related criteria: - third molar - pain >36 on Heft-Parker VAS scale (fig. 1) - subject tooth with a mobility score 2 or more - subject tooth with a periodontal pocket depth DPSI >=3+ - subject tooth with open or incompletely formed root apices - subject tooth that requires a post - subject tooth with a vertical fracture or horizontal fracture extending below the cemento-enamel junction of the tooth - teeth in the same quadrant requiring root canal therapy - teeth with hypersensitive dentine in the same left or right facial half - absence of periapical radiolucency in the presence of tenderness to percussion. - absence of periapical radiolucency in the absence of pulp sensitivity - previous completed (non)surgical (root-canal) treatment on subject tooth - severe swelling originating from affected tooth;Current medication related criteria: - chronic use of pain relief medication - (par)enteral use of bisphosphonates - systemic corticoid therapy;General-health related criteria: - non-odontogenic facial pain - any known infectious diseases (eg, human immunodeficiency virus, hepatitis B, hepatitis C, tuberculosis, or prion induced disease) - history of cancer in the oral-maxillofacial region - history of cancer in the last two years - history of head and/or neck radiation therapy - diabetes mellitus type I, - chronic inflammatory diseases like morbus Crohn or rheumatoid arthritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency and intensity of postoperative pain. Quantity of pain medication taken before and after the root canal treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Periapical lesion size before root canal treatment and one year after root canal treatment. | — |
Countries
The Netherlands
Outcome results
None listed