anxiety disorder fear regulation
Conditions
Interventions
Participants visit the laboratory on two separate days, and receive 40 sec.
slow-repetitive TMS stimulation at 70% of the motor threshold to the right side
of their forehead on one of the days, and
Sponsors
Universiteit Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age between 18 and 45. - Right-handedness. - Written informed consent.
Exclusion criteria
Exclusion criteria: Violation of standard TMS safety criteria (Rossi, Hallett, Rossini, & Pascual-Leone, 2009; see also Appendix F1.1: TMS screenings questionnaire): - Incapability of giving an informed consent - Ferrous objects in or around the head (e.g. braces, pacemaker, metal fragments) - History of closed- or open-head injury - History of epilepsy - History of epilepsy in first-degree relatives - History of neurological or psychiatric illness - Major medical history - Drug or alcohol abuse over a period of six months prior to the experiment - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter for study 1 is the effect of TMS stimulation on the reduction in FPS at offset of a threat cue, for study 2 the increase in SSRT (behaviourally) and concomitant decrease of N1 (derived from the EEG). | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A. | — |
Countries
Netherlands
Outcome results
None listed