Light Adaptation in glaucoma- The influence of dynamic light conditions on visual functioning.

Light Adaptation in glaucoma- The influence of dynamic light conditions on visual functioning. - Light Adaption in glaucoma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45610

Enrollment

Registered

2017-05-24

Start date

2017-08-22

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Glaucoma patients between ages 50 and 75, who visit the Ophthalmology clinic at University Medical Center Groningen, that have provided the informed consent form and meet the inclusion-exclusion criteria. Healthy subjects between ages 50 and 75, who have provided the informed consent form and returned the questionnaire with results which do not indicate ophthalmic abnormalities.

Exclusion criteria

Exclusion criteria: Glaucoma Patients: Visual acuity less than 0.8 Non-glaucomatous visual field loss;Healthy Subjects: Visual acuity less than 0.8 Any visual field loss Intraocular pressure above 21 mmHg Positive family history of glaucoma

Design outcomes

Primary

Measure	Time frame
Contrast gain control as a function of the frequence in which background luminance changes in time. Contrast sensitivity in central and peripheral sites of the retina will be measured by using a staircase method. The contrast gain control will be defined as the difference between the contrast sensitivity measured at static (0 Hz) versus the dynamic light conditions. The contrast gain control can then be compared between the healthy control group and glaucoma patients. We measure contrast gain control at two different values of the mean background luminance and for two polarities (white (increment) and black (decrement) stimuli on a gray background).	—

Measure

Time frame

Contrast gain control as a function of the frequence in which background luminance changes in time. Contrast sensitivity in central and peripheral sites of the retina will be measured by using a staircase method. The contrast gain control will be defined as the difference between the contrast sensitivity measured at static (0 Hz) versus the dynamic light conditions. The contrast gain control can then be compared between the healthy control group and glaucoma patients. We measure contrast gain control at two different values of the mean background luminance and for two polarities (white (increment) and black (decrement) stimuli on a gray background).

—

Secondary

Measure	Time frame
Critical Fusion Frequency (CFF). CFF is the highest frequency at which flicker can be detected. This will be measured in the central and peripheral visual field for a range of background luminances.	—

Countries

Netherlands

Outcome results