mesothelioom Pleural thickening
Conditions
Interventions
mesothelioma
pleural malignancies
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: -*18 years of age -Supected intra-thoracic malignancies with pleural involvement and referred for a diagnostic procedure by thoracoscopy, transthoracic biopsy or endosonography.
Exclusion criteria
Exclusion criteria: -Inability and willingness to provide informed consent - Inability to comply with the study protocol - Patients with known allergy for fluorescein or risk factors for an allergic reaction: - use of betablokker within 12 hours before start of the procedur - possible pregnancy or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - To describe and develop visual descriptive image criteria for CLE images of malignant, normal and fibrotic areas (thoracic wall, pleura, mediastinum) - To obtain quantitative measures by CLE imaging of these malignancies | — |
Secondary
| Measure | Time frame |
|---|---|
| - Assessing technical feasibility of CLE by several approaches used in the process of diagnosis or staging (% of successful videos/time for procedure (min)) - Assessing procedure-related adverse events of CLE in this group of patients | — |
Countries
The Netherlands
Outcome results
None listed