chronic bronchitis chronic obstructive pulmonary disease (COPD) emphysema
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Older healthy adults: - Healthy subjects - Aged between 50-80 years old - No known musculoskeletal disease, condition or injury that could negatively affect walking or balance ability - No history of balance problems, dizziness or walking difficulties - Must be able to walk at comfortable speed for 30 minutes without stopping - Informed consent given;Patients with COPD - Main diagnosis is COPD, diagnosed at CIRO (FEV1/FVC
Exclusion criteria
Exclusion criteria: - musculoskeletal disease, condition or injury - subject is unable to walk without walking aids - subject is unable to perform the 6-minute walk test without a stop - subject with open wounds - subject with balance problems, dizziness or walking difficulties (for healthy older adults)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the reactive adaptation potential measured during the locomotor plasticity assessment protocol with the Gait Real-time Analysis Interactive Lab. This will be calculated as the magnitude of change in the margin of stability at touchdown of the first step after the perturbation before and after repetition of the perturbation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Walking speed, step width, step length, cadence at touchdown of the first and following recovery steps after each perturbation. | — |
Countries
The Netherlands