Constipation Fecal obstruction
Conditions
Interventions
Anorectal Function Tests
Anorectum
Defecation
During the second testsession, we will apply the local anaesthetic or placebo
to the anal canal of the participant. After approximately 15 minutes, we will
start with the anorectal function tests.
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: All subjects must be aged > 18 years.
Exclusion criteria
Exclusion criteria: A potential subject with self-report of bowel problems in a checklist, medical history of congenital abnormalities of the anorectal area, neurological dysfunction, current pregnancy and/or trauma or surgery on the gastrointestinal tract or pelvic floor with a possible influence on anorectal function, will be excluded from analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Because we hypothesize that the physiological regulatory mechanisms of anorectal function are located in the anal (sub)mucosa, we will compare all the physiological parameters obtained during anorectal function tests performed under two conditions: with an active superficial anal mucosa, and after its inactivation. In this way we will be able to indicate the regulatory factors, and also prove that that they are located in the anal mucosa or submucosa, which will be the outcome of this study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
The Netherlands
Outcome results
None listed