The impact of timed protein supplementation to maximize the skeletal muscle adaptive response with endurance exercise training in young healthy men

The impact of timed protein supplementation to maximize the skeletal muscle adaptive response with endurance exercise training in young healthy men - Protein supplementation and the skeletal muscle adaptive response

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON45535

Enrollment

Registered

2017-02-16

Start date

2017-03-20

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect van duurtraining met eiwitsuppletie op spier en bloed Not applicable

Interventions

Three times a week endurance training, for a total period of 12 weeks. The exercise sessions in week 6 and 12 will be replaced by other exercise tests. The training sessions last for 30 up to 60 min

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Male * Age between 18 and 30 years of age * BMI between 18.5 * 25 kg/m2 * Recreationally active, performing sports on a non-competitive basis * Wmax * 5 *kg * Willing to give muscle biopsies * Willing to give blood samples * Having a general-practitioner * Consumption of alcohol beverages is less than 21 per week * Able to perform three exercise sessions weekly for 12 weeks

Exclusion criteria

Exclusion criteria: * Medical condition that can interfere with the study outcome (i.e. cardiovascular disease, pulmonary disease, liver or renal disease, diabetes mellitus type 1 or 2) * Having a lactose and/or gluten intolerance * Use of systemic medication (with the exception of antihistaminic medication and the use of occasional painkillers) * (Chronic) injuries of the locomotor system (e.g. musculoskeletal/orthopedic disorders) that can interfere with the intervention * Participants who are enrolled in an interventional biomedical research project or have received an investigational new drug or product with the last 30 days prior to screening. * Smokers and use of illicit drugs * Blood donor during the study and in the three months before start of the study * Employed, or intern, or working on a thesis at the department of Human Nutrition at Wageningen University & Research * Participating in another scientific study (except EetMeetWeet)

Design outcomes

Primary

Measure	Time frame
VO2max	—

Secondary

Measure	Time frame
10-km time trial Muscle Fiber Adaptations capillary density gene expression phosphorylation proteins mitochondrial mass Cytochrome synthesis activity blood parameters body Composition waist circumference body weight BMI	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)