The long-term effect of full-mouth tooth extraction and subsequent implant placement on the oral microflora

The long-term effect of full-mouth tooth extraction and subsequent implant placement on the oral microflora - Full mouth tooth extraction and implant placement

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45370

Enrollment

100

Registered

2017-04-13

Start date

2017-02-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

edentulism toothless

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) The patient is >= 18 years of age; 2) The patient has a hopeless residual dentition of at least 4 teeth for which extraction of all teeth is the only remaining treatment modality. 3) The patient is diagnosed with mild or severe periodontitis (2 approximal sites with at least 2 mm of clinical attachment loss or probing pocket depth of at least 5 mm). 4) The patient is capable of understanding and giving informed consent.

Exclusion criteria

Exclusion criteria: 1) Medical and general contraindications for the surgical procedures; 2) A history of local radiotherapy to the head and neck region; 3) Chemotherapy in the previous 6 months; 4) Systemic or local use of antibiotics in the oral cavity during the last 3 months; 5) Use of anti-septic / antimicrobial therapies (including mouthrinses) in the oral cavity during the last 4 weeks; 6) Patients with dental implants remaining in the oral cavity after full-mouth tooth extraction.

Design outcomes

Primary

Measure	Time frame
Changes in relative abundance of bacterial species over time as analysed by 16S next generation sequencing technique.	—

Countries

Netherlands

Outcome results