Bot metastasen Bone metastases cancer
Conditions
Interventions
The patient is treated once with a targeted irradiation dose of 8 Gy (8000
msV).
Sponsors
Elekta
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Painful bone metastases in the lumbar spine * Radiographic evidence of bone metastases * Histologic proof of malignancy * Karnofsky Performance Score * 50 * Age * 18 years * Able to provide a written informed consent
Exclusion criteria
Exclusion criteria: * Prior radiation therapy within the region planned to be irradiated * Contraindication for MRI according to screening protocol radiology department UMCU (e.g. cardiac pacemakers, and defibrillators, artificial heart valves or cochlear implants, https://richtlijn.mijnumc.nl/Beeld/MRI/Paginas/MRI-Veiligheid-Contra-indicaties.aspx * Claustrophobia * Standard chemotherapy or radionuclide therapy within 48 hours before or after treatment * Any other type of systemic anti-cancer treatment, except for endocrine treatment * Unstable spine requiring surgical stabilization * Neurological deficit * Not able to provide a written informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To confirm in the clinical setting: * Safety of the treatment system * Geometrical accuracy of real-time targeted irradiation with real-time MR imaging | — |
Secondary
| Measure | Time frame |
|---|---|
| * Feasibility of the clinical workflow * Patients (dis)comfort | — |
Countries
Netherlands
Outcome results
None listed