Pharmacokinetics of single-dose administration of paracetamol by nasoduodenal tube throughout childhood

Pharmacokinetics of single-dose administration of paracetamol by nasoduodenal tube throughout childhood - PARADUO

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45360

Enrollment

Registered

2017-06-20

Start date

2017-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pijn of koorts waarbij paracetamol gegeven wordt via de duodenale sonde bij kinderen fever Pain

Interventions

children

duodenal tube

paracetamol

pharmacokinetics

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: parenteral informed consent (children 12-18 years of age also informed consent from themselves) age 0-18 years of age arterial or venous line receiving paracetamol through duodenal tube

Exclusion criteria

Exclusion criteria: no informant consent no ongoing enteral feeding through the nasoduodenal tube no baseline paracetamol sample has been taken before the paracetamol dosage

Design outcomes

Primary

Measure	Time frame
concentration-time profiles of paracetamol. The study parameters will be primary PK parameters (clearance and volume of distribution)	—

Secondary

Measure	Time frame
nvt	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)