Active after Stroke

Active after Stroke - ACTS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45278

Enrollment

Registered

2017-05-24

Start date

2017-09-04

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovasculair accident (CVA) stroke

Interventions

cardiopulmonary capacity

physical activity

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: * Stroke according to the WHO definition * Age over 18 * Able to walk 10 m with supervision (Functional Ambulation Categories * 3) - Be close to completion of the in-patient rehbailitation stay (for patients in the Hoogstraat)

Exclusion criteria

Exclusion criteria: * Severe cognitive disorder (Mini Mental State Examination

Design outcomes

Primary

Measure	Time frame
The primary outcome is the ventilatory anaerobic threshold (VAT). The VAT will be determined as the averages from two independent raters. The VAT can be determined by (1) the point where the V'E/V'O2 reaches its minimum or starts to increase without an increase in the V'E/V'CO2; (2) the point at which the partial pressure of end-tidal oxygen tension (PETO2) reaches a minimum or starts to increase without a decline in the partial pressure of end-tidal carbon dioxide tension (PETCO2); and, (3) the point of deflection of V'CO2versus V'O2 (V-slope method). Oxygen uptake during the ST is assessed with the Cortex Metamax B3 (Cortex Biophysik GmbH, Leipzig, Germany) measuring gas exchange while subjects perform the ST.	—

Measure

Time frame

The primary outcome is the ventilatory anaerobic threshold (VAT). The VAT will be determined as the averages from two independent raters. The VAT can be determined by (1) the point where the V'E/V'O2 reaches its minimum or starts to increase without an increase in the V'E/V'CO2; (2) the point at which the partial pressure of end-tidal oxygen tension (PETO2) reaches a minimum or starts to increase without a decline in the partial pressure of end-tidal carbon dioxide tension (PETCO2); and, (3) the point of deflection of V'CO2versus V'O2 (V-slope method). Oxygen uptake during the ST is assessed with the Cortex Metamax B3 (Cortex Biophysik GmbH, Leipzig, Germany) measuring gas exchange while subjects perform the ST.

—

Secondary

Measure	Time frame
VO2max (ml.kg-1.min-1), defined as a plateau in VO2 or a Respiratory Exchange Rate (RER) of 1.05 for 50-64 year olds and RER 1.0 for those 65 years and older for both males and females as recommended by Edvardsen et al. in addition we will determine the respiratory compensation point or secondary ventilatory threshold (RCP). The RCP can be determined by: (1) the minimal value or nonlinear rise of V'E/V'CO2; (2) the point that PETCO2 starts to decline; and (3) the point of deflection of V'E versus V'CO2. time walked during the test, measured by stopwatch adverse events during the test	—

Measure

Time frame

VO2max (ml.kg-1.min-1), defined as a plateau in VO2 or a Respiratory Exchange Rate (RER) of *1.05 for 50-64 year olds and RER *1.0 for those 65 years and older for both males and females as recommended by Edvardsen et al. in addition we will determine the respiratory compensation point or secondary ventilatory threshold (RCP). The RCP can be determined by: (1) the minimal value or nonlinear rise of V'E/V'CO2; (2) the point that PETCO2 starts to decline; and (3) the point of deflection of V'E versus V'CO2. time walked during the test, measured by stopwatch adverse events during the test

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Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)