Accurate delineation of glioma infiltration by advanced PET/MR neuro-imaging

Accurate delineation of glioma infiltration by advanced PET/MR neuro-imaging - PET/MRI of glioma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45242

Enrollment

Registered

2013-12-18

Start date

2014-08-14

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain tumor

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Adult (18 years and older) * MRI interpretation of diffuse infiltrative glioma by an expert neuroradiologist * Indication for resective surgery confirmed by the multidisciplinary neuro-oncology workgroup * Written informed consent

Exclusion criteria

Exclusion criteria: * Previous brain surgery, cranial radiotherapy or chemotherapy * Other brain pathology on MRI, such as infarction or multiple sclerosis * Tumor located infratentorially or in the spinal cord * Estimated duration of surgery more than 440 minutes * Pregnancy

Design outcomes

Primary

Measure	Time frame
Quantitative and qualitative imaging data from standard MRI (T1 without and with gadolinium, T2, 3D FLAIR), advanced MRI (DTI, perfusion-weighted MRI, MRS) and advanced PET (FET, CHO). Histopathological and molecular characterization of biopsy samples.	—

Countries

Netherlands

Outcome results