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Potential HIV Cure by Stem Cell Transplantation

Potential HIV Cure by Stem Cell Transplantation - IciStem

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON45224
Enrollment
5
Registered
2015-04-14
Start date
2015-04-21
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AIDS HIV

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Stemcel transplantation on clinical indication HIV infected 18 years old

Exclusion criteria

Exclusion criteria: Any patient unable to give informed consent.

Design outcomes

Primary

MeasureTime frame
Description of clinical, virological and immunological data before and after transplantation. Assessment of HIV integration sites to determine whether residual HIV derives from a long lived latent infected cell or from cell proliferation. Assessment of TRECs to distinguish between recent thymic emigrant and the peripheral T cell pool.

Secondary

MeasureTime frame
Assessment of different levels of immune responses

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)