botaandoeningen eosinophilic granuloma histiocytosis X
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with clinical features suspected of LCH (prospective study) or patients with clinically and histocology confirmed LCH with non active disease (retrospective study).
Exclusion criteria
Exclusion criteria: Clinical features which do not lead to the (differential) diagnosis of LCH
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of our study is how certain genes, proteins (or combinations thereof) expressed by LCH-cells or other leasional cells are associated with LCH-free survival or with recurrence of LCH (LCH-reactivation). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are whether or not certain genes, proteins (or combinations thereof) expressed by LCH-cells or other leasional cells are associated with late effects such as neurological or hormonal dysfunction. | — |
Countries
Netherlands
Outcome results
None listed