Does the time between the production of semen and Intra-Uterine Insemination has an impact on pregnancy rates? A prospective randomized clinical trail.

Does the time between the production of semen and Intra-Uterine Insemination has an impact on pregnancy rates? A prospective randomized clinical trail. - Short-long interval semen production-IUI (KLIPSI)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON45103

Enrollment

254

Registered

2011-11-07

Start date

2012-02-07

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subfertiliteit insertion of sperm into the womb Intrauterine insemination

Interventions

Patients are inseminated approximately 3-4 hours after the production of semen (Group I, current practice VUmc) or patients are inseminated approximately 75 minutes after the production of semen (Gr

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients who start their first IUI treatment. All subsequent cycles fall within this study. Patients who start a new IUI treatment after an ongoing pregnancy. Both IUI performed in a natural cycle and stimulated cycles fall within this study. Patients with well-adjusted, non-endocrine hormonal pathology fall within this study.

Exclusion criteria

Exclusion criteria: Patients who have IUI with donorsemen. Patients in which the semen was obtained in a different way than masturbation (bladder irrigation, electrical stimulation). Patients who have less than 0.5 million progressive motile sperm left over after work-up of semen. Patients with polycystic ovarian syndrome (PCOS).

Design outcomes

Primary

Measure	Time frame
Ongoing pregnancy rate per patient couple (positive fetal cardiac activity 10 weeks after IUI).	—

Secondary

Measure	Time frame
Clinical pregnancy rate per IUI cycle (HCG> 50 IU /l at 16 days after IUI). Ongoing pregnancy rate per IUI cycle (positive fetal cardiac activity 10 weeks after IUI). Percentage multiple pregnancies Percentage biochemical pregnancies and abortions Percentage/number of live births	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)