Understanding Hallucinations (part II) - fMRI & EEG

Understanding Hallucinations (part II) - fMRI & EEG - Understanding Hallucinations 2

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45084

Enrollment

325

Registered

2013-10-23

Start date

2013-12-07

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Op het symptoom van hallucinaties in 6 verschillende diagnostische groepen: schizofrenie, Ziekte van Parkinson, Ziekte van Alzheimer, Lewy body dementie, patiënten die slechtziend zijn en patiënten die slechthorend zijn. Hallucinations illusory perceptional experience

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Previous participation in the phenomenology/cognition study 13-059. - Belong to one of the following diagnostic groups: 1.Patients with schizophrenia 2. Patients with Parkinson's disease 3. Patients with Lewy body dementia 4. Patients with Alzheimer's disease 5. Patients with hearing impairment 6.Patients with visual loss - Written informed consent

Exclusion criteria

Exclusion criteria: -

Design outcomes

Primary

Measure	Time frame
The main study endpoints are differences between hallucinating and non-hallucinating participants and between hallucinating individuals of different subtypes in: - resting state correlates as measured with fMRI, namely: connectivity within the DMN and connectivity of the DMN to sensory cortices and the hippocampal-amygdala complex. - EEG spectral analysis, synchronization likelihood, clustering index, path lengths and assortativity. - auditory and visual cortex synchronized burst activations.	—

Measure

Time frame

The main study endpoints are differences between hallucinating and non-hallucinating participants and between hallucinating individuals of different subtypes in: - resting state correlates as measured with fMRI, namely: connectivity within the DMN and connectivity of the DMN to sensory cortices and the hippocampal-amygdala complex. - EEG spectral analysis, synchronization likelihood, clustering index, path lengths and assortativity. - auditory and visual cortex synchronized burst activations.

—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results