chronic heart failure. heart failure
Conditions
Interventions
29 Patients receive a low salt bread (0.1 gram sodium per slice) and another 29
patients receive bread with a normal amount of sodium (0.4 gram sodium per
slice). After six weeks follow up, the grou
Sponsors
Viecuri Medisch Centrum voor Noord-Limburg
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age at least 18 years; Estimated GFR (based on Modification of Diet in Renal Disease (MDRD) calculation) 15-45 ml/min/1.73m2, not receiving RRT CHF NYHA III-IV, stable condition on optimal medical therapy: no medication changes in last two weeks prior to start study. Written informed consent Speak and read Dutch
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Participating in any other interventional research study during the same period Hyponatremia; sodium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is a reduction in daily salt intake, which will be measured by detection of sodium in the urine. There will also be a comparison with the food frequency questionnaire which the patients collect during several days. Our primary hypothesis is that a low sodium intake due to the low sodium bread will lead to an improvement of our secondary study parameters We expect a reduction of daily salt intake of 1.5 gram sodium by an average of 5 slices bread a day. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters will be: - Blood pressure - Protein in the urine - Quality of life - Body weight - Signs of heart failure - NYHA classification - body composition and fluid status (intra en extra cellulair) (this measurement will not be performed in patients wit a pacemaker or ICD) | — |
Countries
Netherlands
Outcome results
None listed