Non-invasive testing to aid in the diagnosis of allergies using fingermark depositions

Non-invasive testing to aid in the diagnosis of allergies using fingermark depositions - Allergy diagnosis using fingermarks

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45058

Enrollment

Registered

2014-03-21

Start date

2015-02-12

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergy hypersensitive

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - rhiniconjunctivitis +/- asthma - allergic symptoms, provocation after contact with trees, grass, mites, dogs and/or cats. - positieve skin pricktest for specific allergen in consistency with symptoms -18 years and older. - mentally competent - no comorbidity which interferes with the skin prick test;control subject: - no rhinoconjunctivitis, asthma of eczema - 18 years or older - mentally competent - no comorbidity - negative skinpricktest

Exclusion criteria

Exclusion criteria: - younger than 18 years - not mentally competent - comorbidity, which interferes with the skinprick test -negative skin prick test

Design outcomes

Primary

Measure	Time frame
Positive reaction after the skin prick test, whereby a drop of a solution containing the allergen is placed on the skin, next to this a serie of needle pricks allows the solution to enter the skin, resulting in a red, raised itchy area (called a wheal). Positive staining after incubation of a specific allergen in the fingermark. Negative reaction after injection of a specific allergen after the skin prick test. Negative staining after incuabation of a specific allergen in the fingermark ( no staining). Determination of specific allergies in as well the intracutaneous skin prick test as the fingermark. Saliva will be used as control --> Increased or no increased level of total IgE	—

Measure

Time frame

Positive reaction after the skin prick test, whereby a drop of a solution containing the allergen is placed on the skin, next to this a serie of needle pricks allows the solution to enter the skin, resulting in a red, raised itchy area (called a wheal). Positive staining after incubation of a specific allergen in the fingermark. Negative reaction after injection of a specific allergen after the skin prick test. Negative staining after incuabation of a specific allergen in the fingermark ( no staining). Determination of specific allergies in as well the intracutaneous skin prick test as the fingermark. Saliva will be used as control --> Increased or no increased level of total IgE

—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Outcome results