Long term follow-up of perichondrial transplants for the repair of cartilage defects in the human knee by 7 tesla MRI

Long term follow-up of perichondrial transplants for the repair of cartilage defects in the human knee by 7 tesla MRI - Perichondrial transplant imaging by 7T MRI

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45034

Enrollment

Registered

2015-05-06

Start date

2016-11-29

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cartilage defect osteochondral defect

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age > 18 years old Underwent perichondrial tranplantation in MUMC or autologous chondrocyte transplantation in Sweden between 1986 and 1996.

Exclusion criteria

Exclusion criteria: - Knee arthroplasty in area of transplant (i.e. total-, hemi- knee arthroplasty) - Major surgery of transplant in the knee (e.g. patellectomy, microfracture) - Osteoartritis (grade 4 kellgren and Lawrence scale) - Systemic diseases (e.g. DM II, Rheumatoid arthritis) - Not able to undergo MRI scanning (metal objects in body, tattoo, etc.)

Design outcomes

Primary

Measure	Time frame
The main study parameter is the difference of cartilage quality between the PT and ACT group assessed by 7T MRI.	—

Secondary

Measure	Time frame
1. Quality of cartilage transplant compared to radiographic Kellgren-Lawrence OA grade. 2. Quality of cartilage transplant compared to functionality of the treated knee; KOOS, ICRS-score 3. Quality of cartilage transplant compared to level of pain in the treated knee; VAS-score	—

Countries

Netherlands

Outcome results