Liver function Hepatobiliary Scintigraphy Scintigraphy (HBS) in combination with Selective Internal Radiation Therapy (SIRT)

Liver function Hepatobiliary Scintigraphy Scintigraphy (HBS) in combination with Selective Internal Radiation Therapy (SIRT) - HBS with SIRT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON45011

Enrollment

Registered

2013-11-25

Start date

2014-01-22

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with hepatocellular carcinoma or liver metastases of other primary who are referred for SIRT. Age * 18 years. Signed informed consent obtained prior to any study-specific procedure.

Exclusion criteria

Exclusion criteria: Age * 18 years. Pregnancy or breastfeeding.

Design outcomes

Primary

Measure	Time frame
The primary endpoint of this study is defined as segmental liver function in treated and untreated lobes expressed as absolute value (%/min/m2) and percentage of total liver function 6 weeks after SIRT; and changes in total liver function after SIRT.	—

Secondary

Measure	Time frame
Secondary endpoint is the correlation of scintigraphic findings with clinical and biochemical parameters such as performance score, Chil-Pugh-Turcotte score and serologic liver function tests collected as part of the routine patient management.	—

Countries

Netherlands

Outcome results