Mentalization-Based Treatment for Psychosis: a randomized controlled trial for outpatients with a nonaffective psychotic disorder.

Mentalization-Based Treatment for Psychosis: a randomized controlled trial for outpatients with a nonaffective psychotic disorder. - MBT-P

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON44966

Enrollment

Registered

2014-06-25

Start date

2014-08-22

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-affective psychotic disorders

Interventions

Mentalization Based Treatment for Psychotic Disorders (MBT-P): MBT-P is a type of MBT that has been specifically designed for patients with non-affective psychotic disorders (NAPD), such as schizophr

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * At least six months of prior treatment, which should include relevant psycho-education regarding nonaffective psychotic disorders (schizophrenia, schizophreniform or schizoaffective disorder (295.x), delusional disorder (297.1), brief psychotic disorder (298.8) or psychotic disorder not otherwise specified (298.9)) * Less than ten years of prior treatment for a nonaffective psychotic disorder. * Age 18-55 * Informed consent

Exclusion criteria

Exclusion criteria: * Intellectual disabilities and/or illiteracy (having attended Dutch MLK or ZMLK education). * A lack of mastery of the Dutch language. * Severe addiction to such an extent that inpatient detoxification is necessary. After detoxification the patient is still eligible for participation in the study.

Design outcomes

Primary

Measure	Time frame
Social functioning, the primary outcome measure, is measured with the Social Functioning Scale	—

Secondary

Measure	Time frame
-Social Cogntition (Mediator Variable): The TAT (Thematic Apperception Test), scored with the SCOR System (Social Cognition and Object Relations System), is used to assess the patients* mentalizing capacity. It assesses a patients emotional differentiation, the affect tone of his/her relationships, reflective functioning, capacity for reality testing, emotional investment in relationships and understanding of social causality. The hinting task is used to asses the quality of patients' Theory of Mind. - Social stress reactivity: Using an Experience Sampling Monitoring (ESM) device called the PsyMate, we will measure changes in mood during stressful social interaction. There will be four consecutive assessments: one assessment before treatment, one assessment during treatment, one assessment directly after treatment and one assessment six months after treatment. Each assessment will last for five days. During these assessments, patients record daily social interactions and the degree of social tension in those situations. Questions pertaining to social stress include: I would rather be alone'and 'I like the present company'. Mood is measured with items such as: 'I feel gloomy' (negative affect) and 'I feel enthousiastic' (positive affect). - Quality of Life: Using the MANSA, the Manchester Short Assessment of quality of life changes in overall life quality of patients are measured - Positive, Negative, Anxious and Depressive Symptoms: anxious and depressive symptoms are assessed by independent bachelor psychology graduates that are blind to treatment allocation and measured with several items of the PANSS (Item G2 and G4; Positive and Negative Syndrome Scale7). The PANSS, is a 30-item, 7-point Likert scale rating instrument developed for the assessment of phenomena associated with schizophrenia. Symptoms over the past week are rated. A Dutch version is used. - Substance abuse: Patients are asked to report the instances of substance (ab)use	—

Measure

Time frame

-Social Cogntition (Mediator Variable): The TAT (Thematic Apperception Test), scored with the SCOR System (Social Cognition and Object Relations System), is used to assess the patients* mentalizing capacity. It assesses a patient*s emotional differentiation, the affect tone of his/her relationships, reflective functioning, capacity for reality testing, emotional investment in relationships and understanding of social causality. The hinting task is used to asses the quality of patients' Theory of Mind. - Social stress reactivity: Using an Experience Sampling Monitoring (ESM) device called the PsyMate, we will measure changes in mood during stressful social interaction. There will be four consecutive assessments: one assessment before treatment, one assessment during treatment, one assessment directly after treatment and one assessment six months after treatment. Each assessment will last for five days. During these assessments, patients record daily social interactions and the degree of social tension in those situations. Questions pertaining to social stress include: *I would rather be alone'and 'I like the present company'. Mood is measured with items such as: 'I feel gloomy' (negative affect) and 'I feel enthousiastic' (positive affect). - Quality of Life: Using the MANSA, the Manchester Short Assessment of quality of life changes in overall life quality of patients are measured - Positive, Negative, Anxious and Depressive Symptoms: anxious and depressive symptoms are assessed by independent bachelor psychology graduates that are blind to treatment allocation and measured with several items of the PANSS (Item G2 and G4; Positive and Negative Syndrome Scale7). The PANSS, is a 30-item, 7-point Likert scale rating instrument developed for the assessment of phenomena associated with schizophrenia. Symptoms over the past week are rated. A Dutch version is used. - Substance abuse: Patients are asked to report the instances of substance (ab)use

—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)