The Influence of the Pre-operative Nociceptive Profile on the Development of Chronic Pain after Inguinal Hernia Repair Surgery

The Influence of the Pre-operative Nociceptive Profile on the Development of Chronic Pain after Inguinal Hernia Repair Surgery - The prepair studie

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44933

Enrollment

500

Registered

2017-11-29

Start date

2015-03-23

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pijngeneeskunde chronic pain neuropathic pain

Interventions

Chronic pain

Endogenous modulation of pain

Inguinal hernia

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - American Society of Anesthesiologists score 1, 2 or 3 - aged 18 to 75 years - planned to undergo elective surgery involving an inguinal hernia repair

Exclusion criteria

Exclusion criteria: (1) Pain scores > 3 (on a 11-point numerical rating scale, NRS) reported for most of the day during the past month; (2) Regular use of analgesics for any purpose, including SNRIs, gabapentinoids, COX inhibitors or NSAIDs during the previous month; (3) The presence of any chronic pain disorder; (4) Inability to perform psychophysical testing (eg. in case of cognitive or psychiatric disorders); (5) Inability to give informed consent; (6) Inability to communicate with the investigators;

Design outcomes

Primary

Measure	Time frame
- endogenous pain modulation: pro-nociceptive profile vs anti-nociceptive profile - development of chronic pain	—

Secondary

Measure	Time frame
Acute pain and analgesic use in the first 24 hours after surgery	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)