International CIDP Outcome Study A prospective study on clinical and biological predictors of disease course and outcome in CIDP

International CIDP Outcome Study A prospective study on clinical and biological predictors of disease course and outcome in CIDP - ICOS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44925

Enrollment

500

Registered

2015-07-17

Start date

2015-11-12

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic inflammatory demyelinating polyneuropathy

Interventions

None listed

Eligibility

Age

2 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. The ICOS is using the EFNS/PNS criteria (clinical and electrophysiological criteria) for the diagnosis of CIDP. Three categories of patients are eligible for the ICOS: a) Patients fulfilling the clinical criteria and the definite, probable or possible electrophysiological criteria defined in supplement 1. b) Patients fulfilling the clinical criteria and at least two supportive criteria defined in supplement 1. c) Patients fulfilling the clinical criteria for pure sensory CIDP and at least two supportive criteria defined supplement 2 (if not fulfilling the electrophysiological criteria). 2. Being able and willing to conduct a follow-up of at least 2 years. 3. Informed consent.

Exclusion criteria

Exclusion criteria: No exclusion criteria

Design outcomes

Primary

Measure	Time frame
ICOS will result in a combined data- and biobank of well defined patients with CIDP. The primary study parameters will include the grip strength measured by using a Vigorimeter or Jamar dynamometer and the Rasch-MRC sum score. Furthermore we will use several standardized validated clinical outcome measure scales such as: Rasch-built Overall Disability Scale(R-ODS), modified INCAT sensory scale, Pain Intensity Rating scale, Rasch-Fatigue Severity Scale(FSS) and EuroQoL-5D questionnaire.	—

Measure

Time frame

ICOS will result in a combined data- and biobank of well defined patients with CIDP. The primary study parameters will include the grip strength measured by using a Vigorimeter or Jamar dynamometer and the Rasch-MRC sum score. Furthermore we will use several standardized validated clinical outcome measure scales such as: Rasch-built Overall Disability Scale(R-ODS), modified INCAT sensory scale, Pain Intensity Rating scale, Rasch-Fatigue Severity Scale(FSS) and EuroQoL-5D questionnaire.

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Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results