unilateral Cerebral Palsy/ spasticity
Conditions
Interventions
MuSSAP
In contrast to the primary focus on motor skill acquisition in functional
training, Multi Sensory Stimulation And Priming (MuSSAP) aims to enhance motor
learning by stimulating the perception
Sponsors
Sint Maartenskliniek
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: * Born preterm suffering from unilateral periventricular haemorrhagic infarction with involvement of the corticospinal tracts * Born term suffering from unilateral middle cerebral artery stroke with involvement of the corticospinal tracts * ±4 months of age (time the infant starts to reach with at least one hand) to 10 months of age (age corrected in case of prematurity)
Exclusion criteria
Exclusion criteria: * Severe epilepsy * Severe sensory impairments (blindness, deafness) * Children with clinical signs of bilateral involvement * Inability of parents to respond to interviews or questionnaires in Dutch * Expected inability of parents to adhere to the home-based protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primairy study parameter aims at development of handfunction. At T0, T1 and T2 the following measure will be performed: * Hand Assessment for Infants (HAI) The HAI is currently being developed at the Karolinska Institute of Stockholm (Sweden; Professor Eliasson and Professor Sundholm) in collaboration with the University of Pisa. The HAI is intended to evaluate the quality of goal-directed manual actions in infants, 3-12 months of age, at risk of developing unilateral CP. The test procedure comprises a semi-structured video-recorded 10-15-min play session. HAI is intended to detect and quantify possible asymmetry between hands by providing scores for each hand seperately, and to provide a measure of bilateral hand use (Eliasson et al. 2014). | — |
Secondary
| Measure | Time frame |
|---|---|
| At T0, T1 and T2, the following measures will be performed: * At T0 the following measures will be performed: Hand function: * Video-Observation Aarts and Aarts; VOAA-baby. To assess both the overall duration and frequency of upper-limb use, the *Video Observations Aarts and Aarts-baby* will be performed. By using structured video observations and a custom-designed software program, the tasks can be scored offline for the occurrence of specific motor behaviours (i.e. frequency) and the total duration of affected upper-limb use (Houwink et al., 2013). The VOAA-baby is in development and has therefore not been used previously in other studies . Brain development: Overall motor development: * Bayley Scales of Infant and Toddler Development -Third Edition- Nederlandse versie (Bayley-III-NL). The motor scale of the Bayley-III-NL will be used to assess motor development (Fine Motor subtest and Gross Motor subtest) (Steenis et al., 2014). * Gross Motor Function Measure (GMFM). Motor performance will additionally be assessed using the Gross Motor Function Meas-urement (GMFM). This test contains eighty-eight items grouped into five dimensions (e.g. lying and rolling, sitting, crawling and kneeling, standing, walking, running and jumping) and is sensitive to motor developmental changes over time. Typically children can perform correctly on all eighty-eight items at the age of five years (Russell et al., 2002). * Infant Motor Profile (IMP). The IMP is a qualitative assessment of motor behaviour in infants 3-18 months of age. The IMP is a video-based assessment of spontaneous motor behaviour of infants. The IMP evaluates motor behaviour in five domains: variation, variability (ability to select strategies), movement fluency, movement symmetry and motor performance (Heineman et al., 2008). A study has showed clear differences in IMP scores throughout infancy between children with and without CP diagnosed at the age of 18 months. It indicated tha | — |
Countries
Netherlands
Outcome results
None listed