Co-morbidities overweight/ Vasculac function markers
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: - Participation in the COACH program - Aged between 6 and 18 years (at time of inclusion) - Overweight or obesity according to International Obesity Task Force (IOTF) criteria;For control group - Aged between 6 and 18 years - Normal weight according to the International Obesity Task Force (IOTF) criteria - Undergo surgery for elective reasons
Exclusion criteria
Exclusion criteria: Retardation Inflammatory disease: auto-immune diseases, inflammatory bowel diseases, hepatitis, dermatitis, nephritis, pancreatitis, gastro-enteritis, vasculitis, salpingitis, arthritis, osteomyelitis, myositis, ear-nose-throat infections Allergic disease: asthma, eczema, hay fever, food allergies Oncologic disease Cystic Fibrosis Type 1 Diabetes Mellitus Congenital metabolic disease Undernutrition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is to examine the difference in micro- and macrovasculature characteristics in children with different weight classifications (lean; overweight; obese; extreme obese; morbid obese). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are differences in lipoprotein profiles, pro-inflammatory, fundus photography and OGTT profiles between different age groups, between lean and overweight/obese children and in relation with the measured micro- and macrovasculature characteristics | — |
Countries
Netherlands
Outcome results
None listed