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How sickening is sitting: experimental evidence

How sickening is sitting: experimental evidence - SOS experimental evidence

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON44870
Enrollment
40
Registered
2015-05-12
Start date
2015-06-11
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

c-peptide C-peptide. Indicators of dysfunction of glucose and triglyceride metabolism: 18-22yr old males with a normal body weight: elevated blood plasma levels of glucose insulin triglyceride and cortisol

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
12 Years to 99 Years

Inclusion criteria

Inclusion criteria: NORMAL WEIGHT MALES: Apparently healthy normal weight (20 subjects) males aged 18-22 years; or overweight/obese (BMI *25/30; 20 subjects) males aged 14-18 years; Dutch or English speaking; Signed informed consent from the participant (males aged 16-18 years) and signed informed consent from the participant and one of his parents (males aged 14-15 years).

Exclusion criteria

Exclusion criteria: Major acute illness/injury; Physical problems that may limit the ability to perform the experiment (i.e. the standing or cycling interruptions or sitting on a stability ball); having diabetes mellitus type II.

Design outcomes

Primary

MeasureTime frame
18-22 YEAR OLD MALES WIHT A NORMAL WEIGHT The main outcomes of this study are the post-prandial responses of plasma levels of C-peptide, glucose, triglycerides and high-sensitive C-reactive protein and pre/post values of cortisol plasma levels. 14-18 YEAR OLD MALES WITH OVERWEIGHT/OBESITY The main outcomes of this study are the post-prandial responses of plasma levels of C-peptide, glucose, and high-sensitive C-reactive protein. For details see document "C2. Amendement".

Secondary

MeasureTime frame
18-22 YEAR OLD MALES WIHT A NORMAL WEIGHT Secondary outcomes of this study are functioning of the autonomic nervous system, sleep-wake patterns, attention/concentration and mood. 14-18 YEAR OLD MALES WITH OVERWEIGHT/OBESITY Secondary outcomes of this study are functioning of the autonomic nervous system and "C2. Amendement". For details see document "C2. Amendement".

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)