Use of lung mechanics to identify the optimal level of positive end-expiratory pressure in mechanically ventilated children with acute lung injury: a pilot study

Use of lung mechanics to identify the optimal level of positive end-expiratory pressure in mechanically ventilated children with acute lung injury: a pilot study - Lung mechanics and volume

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44862

Enrollment

Registered

2013-11-13

Start date

2013-09-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early acute lung injury

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: * weight * 3 kg * presence of indwelling arterial line

Exclusion criteria

Exclusion criteria: * admitted to the neonatal intensive care unit * premature birth with gestational age corrected for post-conceptional age

Design outcomes

Primary

Measure	Time frame
The main study parameter is the level and time course of the end-expiratory lung volume.	—

Secondary

Measure	Time frame
Secondary study parameters include the level and time course of the oxygenation index, the SpO2/FiO2 ratio, respiratory system compliance, lung compliance, transpulmonary pressure, and alveolar dead space fraction.	—

Countries

Netherlands

Outcome results