discogene lage rugklachten discus degeneration low back pain
Conditions
Interventions
None listed
Sponsors
Stichting Rugpoli
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: discogenic low back problems o Aged between 18-65 o Pain exists for a minimum period of 3 months VAS score min. 5. o Pain does not respond to conservative treatment. o Remaining discushight 50% minimum controlled by MRI- of CT scan. o Extrusions of discus are 5 mm or less controlled by MRI- of CT scan. o Positive result on discografie in conformity with Isis Guidelines. [46]
Exclusion criteria
Exclusion criteria: o Modicse changes o pregnancy o Use of anticoagulantia o skin at the puncturespot. o Contrastallergy. o Psychiatric disorder o Solid bonefusion o Severe spinal stenoses at the treatment level. o Extrusions larger than 5mm o Spondylolisthesis level 2 or larger.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The goal for the pilot study is a minimal clinically relevant improvement of 1,5 points NRS en 2 points RMDQ, after 2 months. Based on the priliminary data from the USA the clinical expectance for the patients who receive PRP is for pain from 7 to 5 points NRS in 12 months and for functionality from 12 to 9 points RMDQ in 12 months. For patients in the control group the expectance is half a point NRS 7 to 6.5 and RMDQ from 12 to 11. | — |
Secondary
| Measure | Time frame |
|---|---|
| none | — |
Countries
Netherlands
Outcome results
None listed