The effect of uterine bathing on implantation in endometriosis patients undergoing IVF/ICSI: a randomized controlled pilot trial

The effect of uterine bathing on implantation in endometriosis patients undergoing IVF/ICSI: a randomized controlled pilot trial - TUBIE trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON44836

Enrollment

184

Registered

2014-04-10

Start date

2014-07-22

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subfertile couples with an indication for IVF/ICSI treatment Subfertility with indication for IVF/ICSI

Interventions

Patients will be randomized to undergo uterine bathing through a GIS (intervention group) or a sham procedure (control group) before treatment with IVF/ICSI. The intervention will be performed in th

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Woman between 18 and 41 years old. - Indication for IVF/ICSI (first, second or third attempt) - Endometriosis ASRM stage I-IV - Signed informed consent.

Exclusion criteria

Exclusion criteria: - Women aged over 41 years - Women who are unable to undergo IVF/ICSI - Uterusanomalies (bicornis/didelphys/septa) - Pregnancy - Malignancy

Design outcomes

Primary

Measure	Time frame
Live birth rate after fresh embryo transfer.	—

Secondary

Measure	Time frame
Implantation rate, clinical pregnancy rate, ongoing pregnancy rate, miscarriages rate, ectopic pregnancy rate, multiple pregnancy rate.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)