Back to the beginning * the Amylon study: Serum amylase, urinary amylase and serum lipase for diagnosing acute pancreatitis

Back to the beginning * the Amylon study: Serum amylase, urinary amylase and serum lipase for diagnosing acute pancreatitis - the Amylon study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44831

Enrollment

180

Registered

2014-04-16

Start date

2014-08-22

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreasontstekingsaandoeningen acute inflammation of the pancreas Acute pancreatitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - hospitalized patients with acute onset of persistent, severe, epigastric pain - aged *18 years - able to provide written informed consent

Exclusion criteria

Exclusion criteria: complaints starting more than 7 days before admission chronic kidney disease (MDRD

Design outcomes

Primary

Measure	Time frame
The diagnostic accuracy (AUC/ROC) of serum amylase, serum lipase and urinary amylase for acute pancreatitis per day after onset of symptoms until day 5 and on day 7.	—

Secondary

Measure	Time frame
- difference in diagnostic accuracy (AUC/ROC) after subgroup analyses: different etiology of acute pancreatitis (f.e. alcohol induced, hyperlipidemia induced or biliary acute pancreatitis), and mild versus severe pancreatitis - difference in diagnostic accuracy (AUC/ROC) in urinary amylase versus amylase creatinine clearance ratio - difference in diagnostic accuracy (AUC/ROC) in one solitary pancreatic enzyme versus a combination of enzymes	—

Measure

Time frame

- difference in diagnostic accuracy (AUC/ROC) after subgroup analyses: different etiology of acute pancreatitis (f.e. alcohol induced, hyperlipidemia induced or biliary acute pancreatitis), and mild versus severe pancreatitis - difference in diagnostic accuracy (AUC/ROC) in urinary amylase versus amylase creatinine clearance ratio - difference in diagnostic accuracy (AUC/ROC) in one solitary pancreatic enzyme versus a combination of enzymes

—

Countries

Netherlands

Outcome results