Sensory processing in autism and childhood epilepsy

Sensory processing in autism and childhood epilepsy - SPACE-study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44800

Enrollment

120

Registered

2015-05-06

Start date

2015-08-18

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autism spectrum disorders - autism

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Ability to comply with the protocol-specified procedures for the duration of the study IQ above 70 Written informed consent (and assent if appropriate to local laws and regulations), In case of methylphenidate use, willingness to skip methylphenidate on the testing days For epilepsy groups: Males and females aged 7-12, Diagnosis of epilepsy and ASD symptoms (SRS50+ or diagnosis according to ADOS, or probable/definite difference at SP-NLor behavioral problems indicative of sensory processing problems (problems at school, irritability etc) For ASD group: Males and females aged 7-12, Diagnosis according to ADOS or given by psychiatrist For control group: Males and females aged 7-15, No psychiatric disorder present

Exclusion criteria

Exclusion criteria: Major visual or auditory impairment Presence of severe medical disorder Other (psychiater) disorders other than epilepsy or ASD

Design outcomes

Primary

Measure	Time frame
Primary endpoint: The main outcome parameters are EEG markers: brain evoked P50 suppression, P300, mismatch negativity and absolute resting-state power change.	—

Secondary

Measure	Time frame
Secondary endpoints: Other EEG phenotypes, neurocognitive and behavioural parameters.	—

Countries

Netherlands

Outcome results