Pulsatility in cerebral perforating arteries in patients with lacunar infarction or deep hemorrhage, an explorative 7T MRI study.

Pulsatility in cerebral perforating arteries in patients with lacunar infarction or deep hemorrhage, an explorative 7T MRI study. - PULSATE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44727

Enrollment

Registered

2015-06-12

Start date

2016-03-31

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

deep intracerebral hemorrhage/hemorrhagde in the deep structures of the brain. lacunar infarction/small deep infarction

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Lacunar infarction group: - Clinical lacunar stroke confirmed by imaging, in the last 5 years. Deep ICH group: - Deep spontaneous ICH, compatible with so-called hypertensive hemorrhage or ICH due to SVD, confirmed by imaging, in the last 5 years. Healthy control group: - No history of stroke, transient ischemic attack or cognitive impairment.

Exclusion criteria

Exclusion criteria: All groups: - WHO performance status score * 2. (independent mobility and living) - Currently hospitalized. - MRI contraindications per clinical practice, such as (possible) pregnancy and metal or electronic implants not compatible with (7T) MRI. Control group: - When study images for a control subject as a chance finding show confluent white matter hyperintensities (Fazekas scale > 2), lacunes or ICH the control will be excluded and replaced.

Design outcomes

Primary

Measure	Time frame
Difference in pulsatility of cerebral perforating arteries between patients and healthy controls.	—

Secondary

Measure	Time frame
N.A.	—

Countries

Netherlands

Outcome results