Microbiome and lower respiratory tract infections in children

Microbiome and lower respiratory tract infections in children - Microbiome and LRTI

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44725

Enrollment

975

Registered

2013-02-12

Start date

2013-09-10

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchitis or pneumonia Lower respiratory tract infections

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: All groups: Children * 4 weeks and * 5 years and;Non-severe LRTI group: Hospitalized for a LRTI at a general pediatric ward. ;Severe LRTI group: Hospitalized at the intensive care ward for a severe LRTI;Control group must fulfil all the following criteria: 1. Children matched with LRTI case for age (in years). In addition children

Exclusion criteria

Exclusion criteria: - Severe concomitant disease (severe congenital heart disease, bronchopulmonary dysplasia, prematurity

Design outcomes

Primary

Measure	Time frame
NP microbiome composition and viral presence in the nasopharynx of children hospitalized for a LRTI and in healthy age-and gender-matched controls.	—

Secondary

Measure	Time frame
1.NP microbiome composition and viruses of LRTI cases after recovery. 2.Clinical data from the medical record, routine chest X-ray results and routine laboratory blood parameters of children hospitalized for LRTI. 3.Microbiota in saliva (oral cavity) and faeces (intestines).	—

Countries

Netherlands

Outcome results